Change isn't always better

Change isn't always better

Maintaining the identity of acinar cells in the pancreas could help to prevent the development of pancreatic cancer.

More isn’t always better

The centrosome serves as the primary micro-tubule-organizing center in animal cells and, consequently, functions in many processes, such as migration and formation of the mitotic spindles. The centrosome consists of a pair of centrioles surrounded by pericentriolar material (PCM), the platform for microtubule nucle-ation. The pair of centrioles duplicate once per cell cycle to ensure the equal ...

Is more always better

Is more always better? We address this question in the context of bibliometric indices that aim to assess the scientific impact of individual researchers by counting their number of highly cited publications. We propose a simple model in which the number of citations of a publication depends not only on the scientific impact of the publication but also on other ‘random’ factors. Our model indic...

Exercise: Is More Always Better?

Do greater levels of exercise always promote relatively higher levels of daily energy expenditure and health? Recent studies challenge the traditional assumption that 'more exercise is better' by suggesting daily energy expenditure and health plateaus are reached beyond which incremental gains are minimal.

Medical care--is more always better?